Pharmacological and Pathological Implications of Sigma-1 Receptor in Neurodegenerative Diseases

Originally identified as a potential receptor for opioids, the sigma-1 receptor is now recognized as an intracellular chaperone protein associated with mitochondria-associated membranes at the endoplasmic reticulum (ER). Over the past two decades, extensive research has revealed that the sigma-1 rec...

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Bibliographic Details
Main Authors: Noah Drewes, Xiangwei Fang, Nikhil Gupta, Daotai Nie
Format: Article
Language:English
Published: MDPI AG 2025-06-01
Series:Biomedicines
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Online Access:https://www.mdpi.com/2227-9059/13/6/1409
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