In silico design and evaluation of a multiepitope vaccine against Bordetella pertussis: structural, immunological, and biological properties

In silico design and evaluation of a multiepitope vaccine against Bordetella pertussis: structural, immunological, and biological properties

Abstract Introduction/objectives Despite widespread vaccination, the increasing incidence of pertussis underscores the urgent need for innovative vaccine strategies. This study aims to design and analyze, using in silico methods, a multiepitope protein that incorporates epitopes from the S1 subunit...

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Bibliographic Details
Main Authors: Negar Souod, Hamid Madanchi, Fariborz Bahrami, Saeed Reza Pakzad, Fereshteh Shahcheraghi, Soheila Ajdary
Format: Article
Language:English
Published: BioMed Central 2025-07-01
Series:Genomics & Informatics
Subjects:
Bordetella pertussis
Multiepitope vaccine
Mucosal immunity
C-CPE
Immunoinformatics
Online Access:https://doi.org/10.1186/s44342-025-00049-0
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https://doi.org/10.1186/s44342-025-00049-0

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