Effect of Degree of Substitution and Molecular Weight on Transfection Efficacy of Starch-Based siRNA Delivery System

Effect of Degree of Substitution and Molecular Weight on Transfection Efficacy of Starch-Based siRNA Delivery System

RNA interference (RNAi) is a promising approach for gene therapy in cancers, but it requires carriers to protect and deliver therapeutic small interfering RNA (siRNA) molecules to cancerous cells. Starch-based carriers, such as quaternized starch (Q-Starch), have been shown to be biocompatible and a...

Full description

Saved in:
Bibliographic Details
Main Authors: Amir Regev, Chen Benafsha, Riki Goldbart, Tamar Traitel, Moshe Elkabets, Joseph Kost
Format: Article
Language:English
Published: MDPI AG 2024-10-01
Series:Polysaccharides
Subjects:
degree of substitution
drug delivery
quaternized starch
ionic strength
alpha-amylase
cellular uptake
Online Access:https://www.mdpi.com/2673-4176/5/4/37
Tags: Add Tag
No Tags, Be the first to tag this record!

Internet

https://www.mdpi.com/2673-4176/5/4/37

Similar Items