Terminal complement complexes with or without C9 potentiate antimicrobial activity against Neisseria gonorrhoeae

ABSTRACT The complement cascade is a front-line defense against pathogens. Complement activation generates the membrane attack complex (MAC), a 10–11 nm diameter pore formed by complement proteins C5b through C8 and polymerized C9. The MAC embeds within the outer membrane of Gram-negative bacteria a...

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Bibliographic Details
Main Authors: Evan R. Lamb, Alison K. Criss
Format: Article
Language:English
Published: American Society for Microbiology 2025-05-01
Series:mBio
Subjects:
Online Access:https://journals.asm.org/doi/10.1128/mbio.00141-25
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