Remarkable tumor response to Iruplinalkib in a 14-year-old girl with ALK-positive advanced metastatic non–small-cell lung cancer: a case report

Remarkable tumor response to Iruplinalkib in a 14-year-old girl with ALK-positive advanced metastatic non–small-cell lung cancer: a case report

Targeted therapies for anaplastic lymphoma kinase (ALK) mutations in non-small cell lung cancer (NSCLC) generally extend survival and alleviate symptoms. However, significant tumor reduction or complete remission remains rare. We report a rare case of a 14-year-old girl, whose father and grandfather...

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Bibliographic Details
Main Authors: Jiahao Wang, Qingdi Du, Xueyan Sun, Rong Tao, Zuojuan Zhang, Wei Li, Wenjing Liu, Li Wei, Zongsheng Tian, Xueliang Xu
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-07-01
Series:Frontiers in Oncology
Subjects:
non-small cell lung cancer
ALK fusion gene mutation
Iruplinalkib
targeted therapy
case report
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2025.1645580/full
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https://www.frontiersin.org/articles/10.3389/fonc.2025.1645580/full

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