Exploring the potential pharmacological mechanism of aripiprazole against hyperprolactinemia based on network pharmacology and molecular docking

Abstract The current primary therapeutic approach for schizophrenia is antipsychotic medication, and antipsychotic-induced hyperprolactinemia occurs in 40–80% of patients with schizophrenia. Aripiprazole, an atypical antipsychotic belonging to the quinolinone derivative class, can reduce the likelih...

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Bibliographic Details
Main Authors: Lei Yang, Qiuyu Zhang, Chao Li, Hongjun Tian, Chuanjun Zhuo
Format: Article
Language:English
Published: Nature Portfolio 2024-11-01
Series:Schizophrenia
Online Access:https://doi.org/10.1038/s41537-024-00523-8
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