Metaboloepigenetics: Role in the Regulation of Flow-Mediated Endothelial (Dys)Function and Atherosclerosis

Metaboloepigenetics: Role in the Regulation of Flow-Mediated Endothelial (Dys)Function and Atherosclerosis

Endothelial dysfunction is the main initiating factor in atherosclerosis. Through mechanotransduction, shear stress regulates endothelial cell function in both homeostatic and diseased states. Accumulating evidence reveals that epigenetic changes play critical roles in the etiology of cardiovascular...

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Bibliographic Details
Main Authors: Francisco Santos, Hashum Sum, Denise Cheuk Lee Yan, Alison C. Brewer
Format: Article
Language:English
Published: MDPI AG 2025-03-01
Series:Cells
Subjects:
endothelial dysfunction
atherosclerosis
shear stress
mechanotransduction
epigenetics
metabolism
Online Access:https://www.mdpi.com/2073-4409/14/5/378
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