Regulation of the tagatose catabolic gene cluster and development of a tagatose-inducible expression system in the probiotic Escherichia coli Nissle 1917

Abstract Background The probiotic Escherichia coli Nissle 1917 (EcN) is a promising microbial chassis for therapeutic and industrial applications. However, its broad utility is limited by a lack of reliable inducible gene expression systems that precisely control gene expression. Results We develope...

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Bibliographic Details
Main Authors: Keunha Park, Youngshin Kim, Dohyeon Kim, Su Min Oh, Tae Jeong Koo, Seung Min Yoo, Sung Ho Yoon
Format: Article
Language:English
Published: BMC 2025-07-01
Series:Microbial Cell Factories
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Online Access:https://doi.org/10.1186/s12934-025-02771-4
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