Supraphysiological levels of GDF11 induce striated muscle atrophy

Abstract Growth and differentiation factor (GDF) 11 is a member of the transforming growth factor β superfamily recently identified as a potential therapeutic for age‐related cardiac and skeletal muscle decrements, despite high homology to myostatin (Mstn), a potent negative regulator of muscle mass...

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Bibliographic Details
Main Authors: David W Hammers, Melissa Merscham‐Banda, Jennifer Ying Hsiao, Stefan Engst, James J Hartman, H Lee Sweeney
Format: Article
Language:English
Published: Springer Nature 2017-03-01
Series:EMBO Molecular Medicine
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Online Access:https://doi.org/10.15252/emmm.201607231
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