Deep immunophenotypic dissection and clinical impact of T cells in the follicular lymphoma microenvironment

Deep immunophenotypic dissection and clinical impact of T cells in the follicular lymphoma microenvironment

Follicular lymphoma (FL) is an indolent B cell lymphoma with a heterogenous disease course, and patients may not require immediate treatment upon diagnosis. Scrutiny of its microenvironment may provide key insights into lymphomagenesis and enhancement of therapeutic options. We analyzed the T-cel...

Full description

Saved in:

Bibliographic Details
Main Authors:	Sary El Daker, David Qualls, Andriy Derkach, Samida Beqaj, Leonardo Boiocchi, Venkatraman Seshan, Jeeyeon Baik, Menglei Zhu, Gilles Salles, Ahmet Dogan, Mikhail Roshal, Pallavi Galera
Format:	Article
Language:	English
Published:	Ferrata Storti Foundation 2025-02-01
Series:	Haematologica
Online Access:	https://haematologica.org/article/view/11931
Tags:	Add Tag No Tags, Be the first to tag this record!

Similar Items

Genetic insight into dissecting the immunophenotypes and inflammatory profiles in the pathogenesis of Sjogren syndrome
by: Jingyi Xu, et al.
Published: (2025-01-01)

Immunophenotyping of Posttraumatic Neutrophils on a Routine Haematology Analyser
by: Kathelijne Maaike Groeneveld, et al.
Published: (2012-01-01)

Immunophenotyping in BK Virus Allograft Nephropathy Distinct from Acute Rejection
by: Xue Li, et al.
Published: (2013-01-01)

Cellular and immune landscape of chronic liver diseases: insights from immunophenotyping
by: Shaghayegh Soleimani, et al.
Published: (2025-01-01)

γδ T Cells Cross-Link Innate and Adaptive Immunity in Mycobacterium tuberculosis Infection
by: Serena Meraviglia, et al.
Published: (2011-01-01)

Spontaneous Apoptosis, Oxidative Status and Immunophenotype Markers in Blood Lymphocytes of AIDS Patients
by: Gabriele A. Losa, et al.
Published: (2000-01-01)

IL-17 Genetic and Immunophenotypic Evaluation in Chronic Graft-versus-Host Disease
by: Renata Gonçalves Resende, et al.
Published: (2014-01-01)

High-parameter immunophenotyping reveals distinct immune cell profiles in pruritic dogs and cats
by: Erin McDonald, et al.
Published: (2025-01-01)

Connexin 43 Communication Channels in Follicular Dendritic Cell Development and in Follicular Lymphomas
by: Hajnalka Rajnai, et al.
Published: (2015-01-01)

Follicular Occlusion Syndrome — a Possible Option of Follicular-Retension Origin of Pilonidal Sinus
by: D. D. Shlyk, et al.
Published: (2024-01-01)

Characterization of Follicular Atresia Responsive to BPA in Zebrafish by Morphometric Analysis of Follicular Stage Progression
by: M. Migliaccio, et al.
Published: (2018-01-01)

Challenges in Preoperative Diagnosis for Thyroid Nodules Classified as Follicular Lesions of Undetermined Significance or Follicular Neoplasms
by: Jeong Seon Park
Published: (2025-01-01)

The role of TRECs/KRECs as immune indicators that reflect immunophenotypes and predict the risk of infection in systemic autoimmune diseases
by: Takuji Itakura, et al.
Published: (2025-02-01)

A Challenging Case of Metastatic Intra-Abdominal Synovial Sarcoma with Unusual Immunophenotype and Its Differential Diagnosis
by: Yi-Che Changchien, et al.
Published: (2012-01-01)

Associations among immunophenotype, plasma metabolites, and benign prostatic hyperplasia: a mediation Mendelian randomization study
by: FAN Jiuming, et al.
Published: (2025-01-01)

Targeted dual biologic therapy for erythroderma of unknown etiology guided by high-parameter peripheral blood immunophenotyping
by: Hannah L. Cornman, et al.
Published: (2025-01-01)

Langerhans Cell Sarcoma: A Case Report Demonstrating Morphological and Immunophenotypical Variability within a Single Lesion
by: Rasika Singh, et al.
Published: (2017-01-01)

Peripheral Regulatory Cells Immunophenotyping in Kidney Transplant Recipients with Different Clinical Profiles: A Cross-Sectional Study
by: Janette Furuzawa-Carballeda, et al.
Published: (2012-01-01)

CAR-T CELL THERAPY FOR FOLLICULAR LYMPHOMAS
by: Ugo Testa, et al.
Published: (2024-01-01)

Mixed Medullary-Follicular Carcinoma of the Thyroid
by: Maasumeh Tohidi, et al.
Published: (2013-01-01)

Embolic Stroke due to a Common Carotid Artery Thrombus in a Young Patient with Severe Iron-Deficiency Anemia without Thrombocytosis
by: David Roshal
Published: (2016-01-01)

Mixed Medullary and Follicular Thyroid Carcinoma (MMFTC)
by: Hasnaini Hasnaini, et al.
Published: (2020-11-01)

Follicular Regulatory T Cells in Systemic Lupus Erythematosus
by: Xin Xia, et al.
Published: (2021-01-01)

Follicular Lymphoma In Situ Presenting as Dermatopathic Lymphadenopathy
by: Orah Nnamdi Obumneme, et al.
Published: (2013-01-01)

Morphological and immunohistochemical analysis in encapsulated follicular variant papillary thyroid carcinoma, invasive follicular variant papillary thyroid carcinoma and a new entity: non-invasive follicular thyroid neoplasm with papillary nuclear feature
by: Zeliha Çelik, et al.
Published: (2024-12-01)

Immunophenotypic Characterization of Human Bone Marrow Mast Cells. A Flow Cytometric Study of Normal and Pathological Bone Marrow Samples
by: Luis Escribano, et al.
Published: (1998-01-01)

HIF-1α and VEGF Immunophenotypes as Potential Biomarkers in the Prognosis and Evaluation of Treatment Efficacy of Atherosclerosis: A Systematic Review of the Literature
by: Dimitra P. Vageli, et al.
Published: (2025-01-01)

Deep immunophenotyping of circulating immune cells in major depressive disorder patients reveals immune correlates of clinical course and treatment response
by: Fabiola Stolfi, et al.
Published: (2025-02-01)

The Function of T Follicular Helper Cells in the Autoimmune Liver Diseases
by: Lin Li, et al.
Published: (2020-01-01)

A Case of Tumor of Follicular Infundibulum Involving the Vulva
by: Victor Santiago, et al.
Published: (2019-01-01)

Impact of NRAS Mutations on the Diagnosis of Follicular Neoplasm of the Thyroid
by: Ja-Seong Bae, et al.
Published: (2014-01-01)

Follicular Helper CD4+ T Cells, Follicular Regulatory CD4+ T Cells, and Inducible Costimulator and Their Roles in Multiple Sclerosis and Experimental Autoimmune Encephalomyelitis
by: Xue Zhang, et al.
Published: (2021-01-01)

Proximity extension assay revealed novel inflammatory biomarkers for follicular development and ovarian function: a prospective controlled study combining serum and follicular fluid
by: Chong Wang, et al.
Published: (2025-02-01)

T-Cell Large Granular Lymphocytic Leukemia with Extremely Rare Immunophenotype (CD4/CD8 Double-Positive) Followed by Multiple Myeloma Diagnosis
by: Dina Soliman, et al.
Published: (2020-01-01)

Pancreatic Inflammatory Pseudotumor-Like Follicular Dendritic Cell Tumor
by: Madison Mograbi, et al.
Published: (2019-01-01)

Paraneoplastic Pemphigus Associated with Follicular Dendritic Cell Tumor in the Mediastinum
by: Aparna Mullangath Prakasan, et al.
Published: (2016-01-01)

Chlamydia trachomatis Mimicking COVID-19 Chronic Follicular Conjunctivitis
by: Sukhmandeep Kaur, et al.
Published: (2021-01-01)

Extensive Spiculated Follicular Porokeratosis With Alopecia: A Case Report
by: Mitra Abdolvand, et al.
Published: (2025-01-01)

Ultrasound Findings Suggestive of Malignancy in Thyroid Nodules Classified as Follicular Lesion of Undetermined Significance or Follicular Neoplasm based on the 2017 Bethesda System for Reporting Thyroid Cytopathology
by: Heui Jin Jung, et al.
Published: (2025-01-01)

Mantle Cell Lymphoma in the Thyroid: A Rare Presentation
by: Uzma Mohammad Siddiqui, et al.
Published: (2017-01-01)