Centromere positioning orchestrates telomere bouquet formation and the initiation of meiotic differentiation
Abstract Accurate gametogenesis requires the establishment of the telomere bouquet, an evolutionarily conserved, 3D chromosomal arrangement. In this spatial configuration, telomeres temporarily aggregate at the nuclear envelope during meiotic prophase, which facilitates chromosome pairing and recomb...
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Main Authors: | Alberto Jiménez-Martín, Alberto Pineda-Santaella, Rebeca Martín-García, Rodrigo Esteban-Villafañe, Alix Matarrese, Jesús Pinto-Cruz, Sergio Camacho-Cabañas, Daniel León-Periñán, Antonia Terrizzano, Rafael R. Daga, Sigurd Braun, Alfonso Fernández-Álvarez |
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Format: | Article |
Language: | English |
Published: |
Nature Portfolio
2025-01-01
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Series: | Nature Communications |
Online Access: | https://doi.org/10.1038/s41467-025-56049-9 |
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