Combined transcriptome and metabolome analysis of stable knockdown and overexpression of the CD8A gene in chicken T lymphocytes

Combined transcriptome and metabolome analysis of stable knockdown and overexpression of the CD8A gene in chicken T lymphocytes

CD8 subunit alpha (CD8A) is an important gene in immunity and is involved in the functional regulation of T lymphocytes. However, the specific role and regulatory mechanism of CD8A in chicken T lymphocytes remain unknown. In this study, we overexpressed and interfered with CD8A in chicken T lymphocy...

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Bibliographic Details
Main Authors: Yanli Du, Kun Wang, Xiannian Zi, Xiao Wang, Meiquan Li, Bo Zhang, Jinshan Ran, Wei Huang, Jing Wang, Cuilian Dong, Hanyi Xiang, Li Lei, Changrong Ge, Yong Liu
Format: Article
Language:English
Published: Elsevier 2025-02-01
Series:Poultry Science
Subjects:
CD8A
Interference
Overexpression
Transcriptome analysis
Metabolome analysis
Online Access:http://www.sciencedirect.com/science/article/pii/S0032579124012641
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http://www.sciencedirect.com/science/article/pii/S0032579124012641

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