Comparison of the CH and OH Groups as Proton Donors within Hydrogen Bonds

The ability of the CH group to act as proton donor is now widely accepted, even if the H bonds (HBs), which it forms are typically much weaker than those of the hydroxyl group, particularly for a sp3‐hybridized C. An NH3 nucleophile is allowed to approach both the terminal methyl group and the hydro...

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Bibliographic Details
Main Authors: Savannah Rawlings, Steve Scheiner
Format: Article
Language:English
Published: Wiley-VCH 2025-07-01
Series:ChemistryEurope
Subjects:
Online Access:https://doi.org/10.1002/ceur.202500088
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