Exploring heat shock protein-related biomarkers and subgroups in osteoarthritis using Gene Expression Omnibus data sets

Exploring heat shock protein-related biomarkers and subgroups in osteoarthritis using Gene Expression Omnibus data sets

Abstract Osteoarthritis (OA) is a degenerative joint disease marked by cartilage deterioration. Recent studies suggest that heat shock proteins (HSPs) may play a role in the pathophysiology of OA. This study explores the role of heat shock protein-related genes (HSRs) in OA using GEO datasets (GSE12...

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Bibliographic Details
Main Authors: Weixin Cai, Boxin Yan, Hanbing Song, Jiaxing Liu, Geqiang Wang, Yichang Jiang
Format: Article
Language:English
Published: BMC 2025-06-01
Series:BMC Musculoskeletal Disorders
Subjects:
Heat shock protein
Bioinformatics
Osteoarthritis
Immune cell infiltration
SsGSEA
Disease subgroups
Online Access:https://doi.org/10.1186/s12891-025-08827-1
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https://doi.org/10.1186/s12891-025-08827-1

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