Quorum quenching by Est816: a novel approach to control Porphyromonas gingivalis pathogenicity
Abstract Background Porphyromonas gingivalis (P. gingivalis), a keystone pathogen in peri-implantitis, employs quorum sensing (QS) via N-acyl homoserine lactones (AHLs) to regulate biofilm formation and virulence. Quorum-quenching enzymes, such as the AHL-lactonase Est816, offer a promising therapeu...
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| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
BMC
2025-07-01
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| Series: | BMC Oral Health |
| Subjects: | |
| Online Access: | https://doi.org/10.1186/s12903-025-06563-5 |
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