Integrative analysis of semaphorins family genes in colorectal cancer: implications for prognosis and immunotherapy

Integrative analysis of semaphorins family genes in colorectal cancer: implications for prognosis and immunotherapy

BackgroundSemaphorins (SEMAs), originally identified as axon guidance factors, have been found to play crucial roles in tumor growth, invasiveness, neoangiogenesis, and the modulation of immune responses. However, the prognostic value of SEMA-related genes in colorectal cancer (CRC) remains unclear....

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Bibliographic Details
Main Authors: Jiahao Zhu, Benjie Xu, Zhixing Wu, Zhiwei Yu, Shengjun Ji, Jie Lian, Haibo Lu
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-03-01
Series:Frontiers in Immunology
Subjects:
semaphorins
colorectal cancer
immunotherapy
single-cell sequencing
spatial transcriptome sequencing
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2025.1536545/full
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https://www.frontiersin.org/articles/10.3389/fimmu.2025.1536545/full

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