Transcriptional Regulation of NUPR1 by MYH11 Activates PI3 K/AKT and Promotes Bladder Cancer Progression Through Ferroptosis and M2 Polarization of Macrophages

Transcriptional Regulation of NUPR1 by MYH11 Activates PI3 K/AKT and Promotes Bladder Cancer Progression Through Ferroptosis and M2 Polarization of Macrophages

Background NUPR1 is a small molecule protein that plays an important role in tumor progression and drug resistance. Our previous study found that NUPR1 promotes the progression of bladder cancer, but the specific mechanism is still unclear. MYH11 encodes the smooth muscle myosin heavy chain and belo...

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Main Authors: Lifeng Zhang DD, Li Zhang BD, Zebin Shi BD, Yuanyuan Mi DD, Lei Zhang MD, Xiaokai Shi MD, Shenglin Gao DD, Li Zuo DD
Format: Article
Language:English
Published: SAGE Publishing 2025-02-01
Series:Technology in Cancer Research & Treatment
Online Access:https://doi.org/10.1177/15330338241305434
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https://doi.org/10.1177/15330338241305434

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