Exploring possible hub genes of metabolic syndrome and type 2 diabetes mellitus: a systematic network biology study

Exploring possible hub genes of metabolic syndrome and type 2 diabetes mellitus: a systematic network biology study

Abstract Metabolic syndrome (MetS) and Type-2 diabetes mellitus (T2DM), often termed “glucolipotoxicity” or insulin resistance syndrome, are complex metabolic disorders typically managed by lifestyle interventions and oral hypoglycemic agents. While conventional drugs, including metformin, sulfonylu...

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Bibliographic Details
Main Authors: Ashish Runthala, Srinivasa R. Vulichi, Sreya Kosanam, Rajeshwari Pasupula, Kakarla Ramakrishna, Monoj Sutradhar, Kumar Pranav Narayan
Format: Article
Language:English
Published: Nature Portfolio 2025-07-01
Series:Scientific Reports
Subjects:
Metabolic syndrome
Type 2 diabetes mellitus
Network Pharmacology
Gene ontology
Multi-Targeting
Online Access:https://doi.org/10.1038/s41598-025-95439-3
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https://doi.org/10.1038/s41598-025-95439-3

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