METTL3 promotes peritoneal metastasis of colorectal cancer through regulating m6A modification of NRXN3 mRNA

METTL3 promotes peritoneal metastasis of colorectal cancer through regulating m6A modification of NRXN3 mRNA

Summary: Colorectal cancer (CRC) is a prevalent digestive system malignancy accompanied by peritoneal metastasis occurring in 7% of cases. Methyltransferase-like 3 (METTL3) promoted the progression of CRC whereas its function in peritoneal metastasis was incompletely understood. Here, we found that...

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Bibliographic Details
Main Authors: Tian-Hao Lan, Wei Li, Xin Wang, Yan-Jie Geng, Bo Pang, Long-Fei Kang, Dong-Yun Li, Li-Yun Pang, Xin-Xin Zhang, Chen-Qi Zhang, Gui-Qi Wang, Zhong-Xin Li, Chuan-Min Zhou, Xia Jiang, Zeng-Ren Zhao
Format: Article
Language:English
Published: Elsevier 2025-08-01
Series:iScience
Subjects:
Biological sciences
Molecular biology experimental approach
Cancer systems biology
Cancer
Online Access:http://www.sciencedirect.com/science/article/pii/S2589004225014269
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http://www.sciencedirect.com/science/article/pii/S2589004225014269

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