Allelic expression patterns of imprinted and non-imprinted genes in cancer cell lines from multiple histologies

Abstract Background Imprinted genes are epigenetically regulated in normal tissues to follow monoallelic expression according to the parent of origin of each allele. Some of these patterns are dysregulated in cancer. Results We developed a novel computational multi-omic pipeline to evaluate monoalle...

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Bibliographic Details
Main Authors: Julia Krushkal, Travis L. Jensen, George Wright, Yingdong Zhao
Format: Article
Language:English
Published: BMC 2025-05-01
Series:Clinical Epigenetics
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Online Access:https://doi.org/10.1186/s13148-025-01883-3
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