Plasma membrane and nuclear phosphatidylinositol 4,5-bisphosphate signalling in cancer
Abstract The development of metastasis is a leading cause of cancer-related death that involves specific changes in the plasma membrane (PM) and nucleus of cancer cells. Elevated levels of membrane lipids, including sphingomyelin, cholesterol, and phosphatidylinositol 4,5-bisphosphate (PI(4,5)P2), i...
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Main Authors: | Agnieszka Chytła, Stephanie Rattay, Baki Akgül, Martin Sztacho |
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Format: | Article |
Language: | English |
Published: |
BMC
2025-02-01
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Series: | Lipids in Health and Disease |
Subjects: | |
Online Access: | https://doi.org/10.1186/s12944-025-02452-6 |
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