Plasma membrane and nuclear phosphatidylinositol 4,5-bisphosphate signalling in cancer

Abstract The development of metastasis is a leading cause of cancer-related death that involves specific changes in the plasma membrane (PM) and nucleus of cancer cells. Elevated levels of membrane lipids, including sphingomyelin, cholesterol, and phosphatidylinositol 4,5-bisphosphate (PI(4,5)P2), i...

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Bibliographic Details
Main Authors: Agnieszka Chytła, Stephanie Rattay, Baki Akgül, Martin Sztacho
Format: Article
Language:English
Published: BMC 2025-02-01
Series:Lipids in Health and Disease
Subjects:
Online Access:https://doi.org/10.1186/s12944-025-02452-6
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