Identification of the Cellular Tipping Point in the Inflammation Model of LPS-Induced RAW264.7 Macrophages Through Raman Spectroscopy and the Dynamical Network Biomarker Theory

Identification of the Cellular Tipping Point in the Inflammation Model of LPS-Induced RAW264.7 Macrophages Through Raman Spectroscopy and the Dynamical Network Biomarker Theory

Raman spectroscopy is a non-destructive spectroscopic technique that provides complex molecular information. It is used to examine the physiological and pathological responses of living cells, such as differentiation, malignancy, and inflammation. The responses of two cellular states, initial and fu...

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Main Authors: Akinori Taketani, Shota Koshiyama, Takayuki Haruki, Shota Yonezawa, Jun Tahara, Moe Yamazaki, Yusuke Oshima, Akinori Wada, Tsutomu Sato, Keiichi Koizumi, Isao Kitajima, Shigeru Saito
Format: Article
Language:English
Published: MDPI AG 2025-02-01
Series:Molecules
Subjects:
DNB theory
inflammation model
Raman spectroscopy
tipping point
tryptophan
Online Access:https://www.mdpi.com/1420-3049/30/4/920
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