Pregnancy in Sickle Cell Disease Is a Very High-Risk Situation: An Observational Study
Sickle cell disease is a serious genetic disorder affecting 1/235 births in French Guiana. This study aimed to describe the follow-up of pregnancies among sickle cell disease patients in Cayenne Hospital, in order to highlight the most reported complications. 62 records of pregnancies were analyzed...
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| Format: | Article |
| Language: | English |
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Wiley
2016-01-01
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| Series: | Obstetrics and Gynecology International |
| Online Access: | http://dx.doi.org/10.1155/2016/9069054 |
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| author | Narcisse Elenga Aurélie Adeline John Balcaen Tania Vaz Mélanie Calvez Anne Terraz Laetitia Accrombessi Gabriel Carles |
| author_facet | Narcisse Elenga Aurélie Adeline John Balcaen Tania Vaz Mélanie Calvez Anne Terraz Laetitia Accrombessi Gabriel Carles |
| author_sort | Narcisse Elenga |
| collection | DOAJ |
| description | Sickle cell disease is a serious genetic disorder affecting 1/235 births in French Guiana. This study aimed to describe the follow-up of pregnancies among sickle cell disease patients in Cayenne Hospital, in order to highlight the most reported complications. 62 records of pregnancies were analyzed among 44 females with sickle cell disease, between 2007 and 2013. Our results were compared to those of studies conducted in Brazil and Guadeloupe. There were 61 monofetal pregnancies and 2 twin pregnancies, 27 pregnancies among women with SS phenotype, 30 SC pregnancies, and five S-beta pregnancies. The study showed that the follow-up of patients was variable, but no maternal death was found. We also noted that the main maternofetal complications of pregnancies were anemia (36.5%), infection (31.7%), vasoocclusive crisis (20.6%), preeclampsia (17.5%), premature birth (11.1%), intrauterine growth retardation (15.9%), abnormal fetal heart rate (14.3%), and intrauterine fetal death (4.8%). Pregnancies were more at risk among women with SS phenotype. Pregnancy in sickle cell disease patients requires a supported multidisciplinary team including the primary care physician, the obstetrician, and the Integrated Center for Sickle Cell Disease. |
| format | Article |
| id | doaj-art-669e610230f942c18c62f111bbf3d2c5 |
| institution | Kabale University |
| issn | 1687-9589 1687-9597 |
| language | English |
| publishDate | 2016-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Obstetrics and Gynecology International |
| spelling | doaj-art-669e610230f942c18c62f111bbf3d2c52025-02-03T05:57:53ZengWileyObstetrics and Gynecology International1687-95891687-95972016-01-01201610.1155/2016/90690549069054Pregnancy in Sickle Cell Disease Is a Very High-Risk Situation: An Observational StudyNarcisse Elenga0Aurélie Adeline1John Balcaen2Tania Vaz3Mélanie Calvez4Anne Terraz5Laetitia Accrombessi6Gabriel Carles7Pediatric Unit, Centre Hospitalier de Cayenne “Andrée Rosemon”, rue des Flamboyants, BP 6006, 97306 Cayenne Cedex, French GuianaIntegrated Center of Sickle Cell Disease (ICS), Centre Hospitalier de Cayenne “Andrée Rosemon”, rue des Flamboyants, BP 6006, 97306 Cayenne Cedex, French GuianaIntegrated Center of Sickle Cell Disease (ICS), Centre Hospitalier de Cayenne “Andrée Rosemon”, rue des Flamboyants, BP 6006, 97306 Cayenne Cedex, French GuianaIntegrated Center of Sickle Cell Disease (ICS), Centre Hospitalier de Cayenne “Andrée Rosemon”, rue des Flamboyants, BP 6006, 97306 Cayenne Cedex, French GuianaIntegrated Center of Sickle Cell Disease (ICS), Centre Hospitalier de Cayenne “Andrée Rosemon”, rue des Flamboyants, BP 6006, 97306 Cayenne Cedex, French GuianaDepartment of Medical Information, Centre Hospitalier de Cayenne “Andrée Rosemon”, rue des Flamboyants, BP 6006, 97306 Cayenne Cedex, French GuianaObstetrics and Gynecology Unit, Centre Hospitalier de Cayenne “Andrée Rosemon”, rue des Flamboyants, BP 6006, 97306 Cayenne Cedex, French GuianaObstetrics and Gynecology Unit, Centre Hospitalier de l’Ouest Guyanais Franck Joly, 16 boulevard du Général de Gaulle, BP 245, 97393 Saint-Laurent-du-Maroni, French GuianaSickle cell disease is a serious genetic disorder affecting 1/235 births in French Guiana. This study aimed to describe the follow-up of pregnancies among sickle cell disease patients in Cayenne Hospital, in order to highlight the most reported complications. 62 records of pregnancies were analyzed among 44 females with sickle cell disease, between 2007 and 2013. Our results were compared to those of studies conducted in Brazil and Guadeloupe. There were 61 monofetal pregnancies and 2 twin pregnancies, 27 pregnancies among women with SS phenotype, 30 SC pregnancies, and five S-beta pregnancies. The study showed that the follow-up of patients was variable, but no maternal death was found. We also noted that the main maternofetal complications of pregnancies were anemia (36.5%), infection (31.7%), vasoocclusive crisis (20.6%), preeclampsia (17.5%), premature birth (11.1%), intrauterine growth retardation (15.9%), abnormal fetal heart rate (14.3%), and intrauterine fetal death (4.8%). Pregnancies were more at risk among women with SS phenotype. Pregnancy in sickle cell disease patients requires a supported multidisciplinary team including the primary care physician, the obstetrician, and the Integrated Center for Sickle Cell Disease.http://dx.doi.org/10.1155/2016/9069054 |
| spellingShingle | Narcisse Elenga Aurélie Adeline John Balcaen Tania Vaz Mélanie Calvez Anne Terraz Laetitia Accrombessi Gabriel Carles Pregnancy in Sickle Cell Disease Is a Very High-Risk Situation: An Observational Study Obstetrics and Gynecology International |
| title | Pregnancy in Sickle Cell Disease Is a Very High-Risk Situation: An Observational Study |
| title_full | Pregnancy in Sickle Cell Disease Is a Very High-Risk Situation: An Observational Study |
| title_fullStr | Pregnancy in Sickle Cell Disease Is a Very High-Risk Situation: An Observational Study |
| title_full_unstemmed | Pregnancy in Sickle Cell Disease Is a Very High-Risk Situation: An Observational Study |
| title_short | Pregnancy in Sickle Cell Disease Is a Very High-Risk Situation: An Observational Study |
| title_sort | pregnancy in sickle cell disease is a very high risk situation an observational study |
| url | http://dx.doi.org/10.1155/2016/9069054 |
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