Efficacy and safety of polymyxin B sulfate versus colistin sulfate in ICU patients with nosocomial pneumonia caused by carbapenem-resistant Acinetobacter baumannii: a multicenter, propensity score-matched, real-world cohort study

Efficacy and safety of polymyxin B sulfate versus colistin sulfate in ICU patients with nosocomial pneumonia caused by carbapenem-resistant Acinetobacter baumannii: a multicenter, propensity score-matched, real-world cohort study

Abstract Background Despite the widespread use of colistin sulfate (CS) in clinical settings in China over recent years, supported by several studies demonstrating its clinical efficacy, there remains a lack of comparative data on the efficacy and safety of polymyxin B sulfate (PMB) versus CS, speci...

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Bibliographic Details
Main Authors: Wei Bu, Chengyu Wang, Yuan Wu, Peng Zhang, Nengfang Zhang, Ying Han, Xiaona Xu, Sha Li, Yan Cai
Format: Article
Language:English
Published: BMC 2025-03-01
Series:BMC Infectious Diseases
Subjects:
Carbapenem-resistant Acinetobacter baumannii (CRAB)
Nosocomial pneumonia
Polymyxin
Propensity score matching
Online Access:https://doi.org/10.1186/s12879-025-10773-1
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https://doi.org/10.1186/s12879-025-10773-1

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