Allantoin Serves as a Novel Risk Factor for the Progression of MASLD

Allantoin Serves as a Novel Risk Factor for the Progression of MASLD

Uric acid (UA), traditionally recognized as an extracellular antioxidant, exhibits paradoxical associations with metabolic disorders such as metabolic dysfunction-associated steatotic liver disease (MASLD), though its mechanistic contributions remain elusive. Here, we integrate multi-modal evidence...

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Main Authors: Weiqiang Lv, Xueqiang Wang, Zhaode Feng, Cunxiao Sun, Hansen Wu, Mengqi Zeng, Tianlin Gao, Ke Cao, Jie Xu, Xuan Zou, Tielin Yang, Hao Li, Lei Chen, Jiankang Liu, Shanshan Dong, Zhihui Feng
Format: Article
Language:English
Published: MDPI AG 2025-04-01
Series:Antioxidants
Subjects:
MASLD
mendelian randomization
allantoin
uric acid
PPARα
Online Access:https://www.mdpi.com/2076-3921/14/5/500
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https://www.mdpi.com/2076-3921/14/5/500

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