The m6A reader YTHDF2 protects vascular smooth muscle cells against the osteogenic differentiation through targeting Runx2

The m6A reader YTHDF2 protects vascular smooth muscle cells against the osteogenic differentiation through targeting Runx2

Vascular calcification (VC) is an important pathological development progress in chronic kidney disease (CKD) and may increase mortality but lacks effective treatments. N6-methyladenosine (m6A) has been verified to be the most prevalent internal chemical RNA modification in mammalian mRNAs. The M6A-...

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Bibliographic Details
Main Authors: Lanmei Li, Meijuan Cheng, Jingjing Jin, Yunfeng Zhao, Weiwei Bai, Dongxue Zhang, Shenglei Zhang, Yaling Bai, Jinsheng Xu
Format: Article
Language:English
Published: Taylor & Francis Group 2025-12-01
Series:Renal Failure
Subjects:
Vascular calcification
osteoblast phenotypic transition
m6A
YTHDF2
Runx2
Online Access:https://www.tandfonline.com/doi/10.1080/0886022X.2025.2488876
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https://www.tandfonline.com/doi/10.1080/0886022X.2025.2488876

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