Single‑cell RNA sequencing reveals TMEM71 as an immunomodulatory biomarker predicting immune checkpoint blockade response in breast cancer

Single‑cell RNA sequencing reveals TMEM71 as an immunomodulatory biomarker predicting immune checkpoint blockade response in breast cancer

Abstract Background TMEM71 is a poorly characterized transmembrane protein with unclear roles in cancer. This study aimed to explore its prognostic value, immune relevance, and therapeutic implications in breast cancer. Methods We integrated transcriptomic, single-cell RNA-seq, immune infiltration a...

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Bibliographic Details
Main Authors: Boyang Li, Ruonan Lin, Yibo Hua, Binlin Ma, Yi Chen
Format: Article
Language:English
Published: Springer 2025-07-01
Series:Discover Oncology
Subjects:
TMEM71
Breast cancer
Single-cell RNA sequencing
Immune microenvironment
Therapeutic response
Online Access:https://doi.org/10.1007/s12672-025-03068-z
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https://doi.org/10.1007/s12672-025-03068-z

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