Exogenous prion-like proteins and their potential to trigger cognitive dysfunction

Exogenous prion-like proteins and their potential to trigger cognitive dysfunction

Abstract The gut is exposed to a wide range of proteins, including ingested proteins and those produced by the resident microbiota. While ingested prion-like proteins can propagate across species, their implications for disease development remain largely unknown. Here, we apply a multidisciplinary a...

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Main Authors: Jofre Seira Curto, Adan Dominguez Martinez, Genis Perez Collell, Estrella Barniol Simon, Marina Romero Ruiz, Berta Franco Bordés, Paula Sotillo Sotillo, Sandra Villegas Hernandez, Maria Rosario Fernandez, Natalia Sanchez de Groot
Format: Article
Language:English
Published: Springer Nature 2025-05-01
Series:Molecular Systems Biology
Subjects:
Microbiome
Neurodegeneration
Prion Protein
Aggregation
Amyloid
Online Access:https://doi.org/10.1038/s44320-025-00114-4
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https://doi.org/10.1038/s44320-025-00114-4

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