Experimental and Mathematical Model of Platelet Hemostasis Kinetics

Experimental and Mathematical Model of Platelet Hemostasis Kinetics

Upon activation, platelets undergo rapid phenotypic transitions to maintain hemostasis, yet the kinetics governing these transitions remain poorly quantified. We present an integrated experimental and mathematical model describing platelet transitions between resting, activated, aggregating, inhibit...

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Bibliographic Details
Main Authors: Bogdan Gerda, Anastasiya Volkova, Irina Dobrylko, Aleksandra Yu. Andreyeva, Thomas Dandekar, Mikhail A. Panteleev, Stepan Gambaryan, Igor Mindukshev
Format: Article
Language:English
Published: MDPI AG 2025-05-01
Series:Cells
Subjects:
platelets
hemostasis
platelet phenotypes
signaling cascades
mathematical modeling
laser diffraction
Online Access:https://www.mdpi.com/2073-4409/14/9/677
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