Studying gastrulation by invagination: The bending of a cell sheet by mechanical cell properties using 3D deformable cell based simulations.

Studying the bending of a cell sheet in vivo, like invagination in embryos, can be complex due to a multitude of cellular processes and properties that interact with each other. Computer simulations can help to unravel this process. 2D computer simulations, however, lack the ability to take into acc...

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Bibliographic Details
Main Authors: Roland M Dries, Kim Y Renders, Jaap A Kaandorp
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2025-06-01
Series:PLoS Computational Biology
Online Access:https://doi.org/10.1371/journal.pcbi.1013151
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