Phage ORF family recombinases: conservation of activities and involvement of the central channel in DNA binding.

Phage ORF family recombinases: conservation of activities and involvement of the central channel in DNA binding.

Genetic and biochemical evidence suggests that λ Orf is a recombination mediator, promoting nucleation of either bacterial RecA or phage Redβ recombinases onto single-stranded DNA (ssDNA) bound by SSB protein. We have identified a diverse family of Orf proteins that includes representatives implicat...

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Main Authors: Fiona A Curtis, Ali D Malay, Alexander J Trotter, Lindsay A Wilson, Michael M H Barradell-Black, Laura Y Bowers, Patricia Reed, Christopher R T Hillyar, Robert P Yeo, John M Sanderson, Jonathan G Heddle, Gary J Sharples
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0102454
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https://doi.org/10.1371/journal.pone.0102454

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