Discussion on the optimization of personalized medication using information systems based on pharmacogenomics: an example using colorectal cancer
Pharmacogenomics (PGx) is a powerful tool for clinical optimization of drug efficacy and safety. However, due to many factors affecting drugs in the real world, PGx still accounts for a small proportion of actual clinical application scenarios. Therefore, based on the information software, pharmacis...
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| Format: | Article |
| Language: | English |
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Frontiers Media S.A.
2025-01-01
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| Series: | Frontiers in Pharmacology |
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| Online Access: | https://www.frontiersin.org/articles/10.3389/fphar.2024.1516469/full |
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| author | Mengying Yuan Yuankun Zheng Fei Wang Niuniu Bai Niuniu Bai Haoling Zhang Yuan Bian Yuan Bian Hao Liu Hao Liu Xia He Xia He |
| author_facet | Mengying Yuan Yuankun Zheng Fei Wang Niuniu Bai Niuniu Bai Haoling Zhang Yuan Bian Yuan Bian Hao Liu Hao Liu Xia He Xia He |
| author_sort | Mengying Yuan |
| collection | DOAJ |
| description | Pharmacogenomics (PGx) is a powerful tool for clinical optimization of drug efficacy and safety. However, due to many factors affecting drugs in the real world, PGx still accounts for a small proportion of actual clinical application scenarios. Therefore, based on the information software, pharmacists use their professional advantages to integrate PGx into all aspects of pharmaceutical care, which is conducive to promoting the development of personalized medicine. In this paper, the establishment of an information software platform is summarized for the optimization of a personalized medication program based on PGx. Taking colorectal cancers (CRC) as an example, this paper also discusses the role of PGx in different working modes and participation in drug management of CRC patients by pharmacists with the help of information systems. Finally, we summarized the recommendations of different PGx guidelines to provide reference for the follow-up personalized pharmaceutical care. |
| format | Article |
| id | doaj-art-65d0d40e54064bee8d02128397a8f1bb |
| institution | Kabale University |
| issn | 1663-9812 |
| language | English |
| publishDate | 2025-01-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Pharmacology |
| spelling | doaj-art-65d0d40e54064bee8d02128397a8f1bb2025-01-14T05:10:36ZengFrontiers Media S.A.Frontiers in Pharmacology1663-98122025-01-011510.3389/fphar.2024.15164691516469Discussion on the optimization of personalized medication using information systems based on pharmacogenomics: an example using colorectal cancerMengying Yuan0Yuankun Zheng1Fei Wang2Niuniu Bai3Niuniu Bai4Haoling Zhang5Yuan Bian6Yuan Bian7Hao Liu8Hao Liu9Xia He10Xia He11Department of Pharmacy, Sichuan Academy of Medical Sciences and Sichuan Provincial People’s Hospital, University of Electronic Science and Technology of China, Chengdu, ChinaDepartment of Pharmacy, Sichuan Academy of Medical Sciences and Sichuan Provincial People’s Hospital, University of Electronic Science and Technology of China, Chengdu, ChinaDepartment of Pharmacy, Sichuan Academy of Medical Sciences and Sichuan Provincial People’s Hospital, University of Electronic Science and Technology of China, Chengdu, ChinaDepartment of Pharmacy, Sichuan Academy of Medical Sciences and Sichuan Provincial People’s Hospital, University of Electronic Science and Technology of China, Chengdu, ChinaShanxi Bethune Hospital, Shanxi Academy of Medical Sciences, Third Hospital of Shanxi Medical University, Tongji Shanxi Hospital, Taiyuan, ChinaDepartment of Pharmacy, Yuncheng Central Hospital, Yuncheng, ChinaDepartment of Pharmacy, Sichuan Academy of Medical Sciences and Sichuan Provincial People’s Hospital, University of Electronic Science and Technology of China, Chengdu, ChinaPersonalized Drug Therapy Key Laboratory of Sichuan Province, School of Medicine, University of Electronic Science and Technology of China, Chengdu, ChinaDepartment of Pharmacy, Sichuan Academy of Medical Sciences and Sichuan Provincial People’s Hospital, University of Electronic Science and Technology of China, Chengdu, ChinaDepartment of Oncology, Sichuan Academy of Medical Sciences and Sichuan Provincial People’s Hospital, University of Electronic Science and Technology of China, Chengdu, ChinaDepartment of Pharmacy, Sichuan Academy of Medical Sciences and Sichuan Provincial People’s Hospital, University of Electronic Science and Technology of China, Chengdu, ChinaPersonalized Drug Therapy Key Laboratory of Sichuan Province, School of Medicine, University of Electronic Science and Technology of China, Chengdu, ChinaPharmacogenomics (PGx) is a powerful tool for clinical optimization of drug efficacy and safety. However, due to many factors affecting drugs in the real world, PGx still accounts for a small proportion of actual clinical application scenarios. Therefore, based on the information software, pharmacists use their professional advantages to integrate PGx into all aspects of pharmaceutical care, which is conducive to promoting the development of personalized medicine. In this paper, the establishment of an information software platform is summarized for the optimization of a personalized medication program based on PGx. Taking colorectal cancers (CRC) as an example, this paper also discusses the role of PGx in different working modes and participation in drug management of CRC patients by pharmacists with the help of information systems. Finally, we summarized the recommendations of different PGx guidelines to provide reference for the follow-up personalized pharmaceutical care.https://www.frontiersin.org/articles/10.3389/fphar.2024.1516469/fullpharmacogenomicscolorectal cancerpersonalized medicationinformation systempharmaceutical service |
| spellingShingle | Mengying Yuan Yuankun Zheng Fei Wang Niuniu Bai Niuniu Bai Haoling Zhang Yuan Bian Yuan Bian Hao Liu Hao Liu Xia He Xia He Discussion on the optimization of personalized medication using information systems based on pharmacogenomics: an example using colorectal cancer Frontiers in Pharmacology pharmacogenomics colorectal cancer personalized medication information system pharmaceutical service |
| title | Discussion on the optimization of personalized medication using information systems based on pharmacogenomics: an example using colorectal cancer |
| title_full | Discussion on the optimization of personalized medication using information systems based on pharmacogenomics: an example using colorectal cancer |
| title_fullStr | Discussion on the optimization of personalized medication using information systems based on pharmacogenomics: an example using colorectal cancer |
| title_full_unstemmed | Discussion on the optimization of personalized medication using information systems based on pharmacogenomics: an example using colorectal cancer |
| title_short | Discussion on the optimization of personalized medication using information systems based on pharmacogenomics: an example using colorectal cancer |
| title_sort | discussion on the optimization of personalized medication using information systems based on pharmacogenomics an example using colorectal cancer |
| topic | pharmacogenomics colorectal cancer personalized medication information system pharmaceutical service |
| url | https://www.frontiersin.org/articles/10.3389/fphar.2024.1516469/full |
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