Co-option of an endogenous retrovirus (LTR7-HERVH) in early human embryogenesis: becoming useful and going unnoticed

Abstract While it is straightforward to understand why most mutations affecting functional sequence are harmful, how genomic changes result in new beneficial traits is harder to understand. Domestication of transposable elements (TEs) is an important source of both new genes and new regulatory syste...

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Bibliographic Details
Main Authors: Zsuzsanna Izsvák, Jin Ma, Manvendra Singh, Laurence D. Hurst
Format: Article
Language:English
Published: BMC 2025-07-01
Series:Mobile DNA
Online Access:https://doi.org/10.1186/s13100-025-00361-0
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