TGF-β Decreases NK Cell Mobility and Cytotoxic Efficacy in Complex in vitro Models of the Leukemia Microenvironment

TGF-β Decreases NK Cell Mobility and Cytotoxic Efficacy in Complex in vitro Models of the Leukemia Microenvironment

Veronika Švubová,1,2 Lucie Janstová,1 Marek Jedlička,1,2 Eva Mašínová,1,2 Jana Szabová,1 Tereza Feglarová,1 Kateřina Kuglerová,1 Veronika Bosáková,3,4 Barbora Brodská,1 Kristýna Boráková,5 David Kundrát,1 Iva Trsová,1,6 Martina Böhmová,1 Kateřina Ku&a...

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Main Authors: Švubová V, Janstová L, Jedlička M, Mašínová E, Szabová J, Feglarová T, Kuglerová K, Bosáková V, Brodská B, Boráková K, Kundrát D, Trsová I, Böhmová M, Kuželová K, Hrdý J, Gašová Z, Vydra J, Dostálová Merkerová M, Hortová-Kohoutková M, Frič J
Format: Article
Language:English
Published: Dove Medical Press 2025-06-01
Series:ImmunoTargets and Therapy
Subjects:
3D models
acute myeloid leukemia
bone marrow niche
TGFbeta
NK cells
immunotherapy.
Online Access:https://www.dovepress.com/tgf--decreases-nk-cell-mobility-and-cytotoxic-efficacy-in-complex-in-v-peer-reviewed-fulltext-article-ITT
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