Optimization of a Method for the Determination of a Mustard Gas Biomarker in Human Blood Plasma by Liquid Chromatography–Mass Spectrometry

A method for the determination of a mustard gas biomarker (an S-hydroxyethylthioethyl adduct with albumin) in blood plasma was optimized with the use of HPLC with tandem mass-spectrometric detection. This method is based on the hydrolysis of this adduct by the proteinase K enzyme with the formation...

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Bibliographic Details
Main Authors: А. V. Braun, I. V. Rybalchenko, V. N. Fateenkov, М. А. Ponsov, Y. V. Stavitskay, D. V. Oreshkin
Format: Article
Language:Russian
Published: 27 Scientific Centre named after academician N.D. Zelinsky 2023-06-01
Series:Вестник войск РХБ защиты
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Online Access:https://www.nbsprot.ru/jour/article/view/158
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