β2-Chimaerin Deficiency Favors Polyp Growth in the Colon of Apc<sup>Min/+</sup> Mice

A Rho-GTPases are pivotal regulators of key cellular processes implicated in colorectal cancer (CRC) progression, yet the roles of their regulatory proteins, particularly GTPase-activating proteins (GAPs), remain poorly understood. This study focuses on β2-chimaerin, a Rac1-specific GAP, in Apc-driv...

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Bibliographic Details
Main Authors: Eladio A. Velasco-Sampedro, Cristina Sánchez-Vicente, María J. Caloca
Format: Article
Language:English
Published: MDPI AG 2025-02-01
Series:Molecules
Subjects:
Online Access:https://www.mdpi.com/1420-3049/30/4/824
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