Cross-Talk between NOK and EGFR: Juxtamembrane and Kinase domain interactions enhancing STAT3/5 signaling in breast cancer tumorigenesis

Cross-Talk between NOK and EGFR: Juxtamembrane and Kinase domain interactions enhancing STAT3/5 signaling in breast cancer tumorigenesis

Epidermal growth factor receptor (EGFR) plays an important role in the regulation of cell proliferation and migration [1]. It forms a homodimer or heterodimer with other ErbB receptor family members to activate downstream signaling. Emerging evidence indicates that the EGFR activity and downstream s...

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Bibliographic Details
Main Authors: Yinyin Wang, Bingdong Zhang, Chunhua He, Bo Tian, Sihan Liu, Jianghua Li, Jiayu Wang, Shigao Yang, Bingtao Zhu, Xiaoguang Wang, Zhijie Chang, Chenxi Cao
Format: Article
Language:English
Published: Elsevier 2025-02-01
Series:Translational Oncology
Subjects:
EGFR signaling
NOK/STYK1
STAT3
STAT5
breast cancer
Online Access:http://www.sciencedirect.com/science/article/pii/S1936523325000075
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http://www.sciencedirect.com/science/article/pii/S1936523325000075

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