Gating Mechanism for Biased Agonism at Angiotensin II Type 1 Receptors

For the interaction of angiotensin II (AngII) with AngII type 1 receptors (AT<sub>1</sub>R), two potential proton hopping pathways have been identified, each associated with distinct physiological outcomes. The octapeptide AngII (Asp<sup>1</sup>-Arg<sup>2</sup>-Va...

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Bibliographic Details
Main Authors: Graham J. Moore, Harry Ridgway, Laura Kate Gadanec, Vasso Apostolopoulos, Anthony Zulli, John M. Matsoukas
Format: Article
Language:English
Published: MDPI AG 2025-05-01
Series:Molecules
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Online Access:https://www.mdpi.com/1420-3049/30/11/2399
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