Interferon epsilon is produced in the testis and protects the male reproductive tract against virus infection, inflammation and damage.

The testis is a reservoir for viruses that can cause persistent infection and adversely affect male reproductive health, an observation commonly attributed to deficiencies in inducible antiviral defence mechanisms. In this study, we demonstrate that interferon-epsilon (IFNε), a type I interferon ini...

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Main Authors: Rukmali Wijayarathna, Eveline D de Geus, Rosemary Genovese, Linden J Gearing, Georgie Wray-McCann, Rajini Sreenivasan, Hiba Hasan, Monika Fijak, Peter Stanton, Daniela Fietz, Adrian Pilatz, Hans-Christian Schuppe, Michelle D Tate, Paul J Hertzog, Mark P Hedger
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2024-12-01
Series:PLoS Pathogens
Online Access:https://doi.org/10.1371/journal.ppat.1012702
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