Therapeutic effects of melittin on paclitaxel-induced peripheral neuropathic pain and spinal neuronal hyperactivity in male rats

IntroductionAs a taxane-based cytostatic agent, paclitaxel holds a broad spectrum of life-saving properties. However, its use is frequently limited by painful neuropathy in the extremities, which severely hinders the ultimate prognosis of cancer survivors. While bee venom therapy has shown promise i...

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Bibliographic Details
Main Authors: Daxian Li, Yan Wu, Lirong Chang, Yizhi Song, Xiaoqiang Du, Fenqin Xue, Yang Liu, Jie Wu, Tianlong Wang
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-07-01
Series:Frontiers in Neuroscience
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Online Access:https://www.frontiersin.org/articles/10.3389/fnins.2025.1622553/full
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