Norovirus regulation of the innate immune response and apoptosis occurs via the product of the alternative open reading frame 4.

Norovirus regulation of the innate immune response and apoptosis occurs via the product of the alternative open reading frame 4.

Small RNA viruses have evolved many mechanisms to increase the capacity of their short genomes. Here we describe the identification and characterization of a novel open reading frame (ORF4) encoded by the murine norovirus (MNV) subgenomic RNA, in an alternative reading frame overlapping the VP1 codi...

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Bibliographic Details
Main Authors: Nora McFadden, Dalan Bailey, Guia Carrara, Alicia Benson, Yasmin Chaudhry, Amita Shortland, Jonathan Heeney, Felix Yarovinsky, Peter Simmonds, Andrew Macdonald, Ian Goodfellow
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-12-01
Series:PLoS Pathogens
Online Access:https://journals.plos.org/plospathogens/article/file?id=10.1371/journal.ppat.1002413&type=printable
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https://journals.plos.org/plospathogens/article/file?id=10.1371/journal.ppat.1002413&type=printable

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