Evaluation of Hippocampal Microanatomy and Neuro-Biomarkers Following Administration of Silver Nanoparticles Conjugated with Tenofovir Disoproxil Fumarate in Experimental Diabetic Rats

Evaluation of Hippocampal Microanatomy and Neuro-Biomarkers Following Administration of Silver Nanoparticles Conjugated with Tenofovir Disoproxil Fumarate in Experimental Diabetic Rats

Adverse complications like metabolic disorders, neurotoxicity, and low central nervous system (CNS) penetration are associated with the long-term use of tenofovir disoproxil fumarate (TDF). Therefore, some modifications are required to enhance neurological functions using silver nanoparticles (AgNPs...

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Main Authors: Sodiq Kolawole Lawal, Samuel Oluwaseun Olojede, Babatunde Adebola Alabi, Kafalotse Sylvia Dithole, Samuel Thopho Matula, Edwin Coleridge Naidu, Carmen Olivia Rennie, Onyemaechi Okpara Azu
Format: Article
Language:English
Published: MDPI AG 2024-12-01
Series:Pharmaceuticals
Subjects:
tenofovir
silver nanoparticles
neurotoxicity
metabolic disorder
microanatomy
diabetes
Online Access:https://www.mdpi.com/1424-8247/17/12/1635
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