Matrix Metalloproteinase‐Responsive Controlled Release of Self‐Assembly Nanoparticles Accelerates Heart Valve Regeneration In Situ by Orchestrating Immunomodulation

Matrix Metalloproteinase‐Responsive Controlled Release of Self‐Assembly Nanoparticles Accelerates Heart Valve Regeneration In Situ by Orchestrating Immunomodulation

Abstract In situ tissue engineering heart valves (TEHVs) are the most promising way to overcome the defects of existing valve prostheses. Despite their promising prospects, the clinical translation of TEHVs remains a formidable challenge, mainly due to unpredictable host interactions post‐implantati...

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Bibliographic Details
Main Authors: Xing Chen, Yunlong Wu, Peng Song, Liandong Feng, Ying Zhou, Jiawei Shi, Nianguo Dong, Weihua Qiao
Format: Article
Language:English
Published: Wiley 2025-01-01
Series:Advanced Science
Subjects:
hydrogel
macrophage polarization
microRNA
nanoparticles
tissue engineering heart valves
Online Access:https://doi.org/10.1002/advs.202403351
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