Clinically directed initiation versus routine use of amoxicillin-clavulanate and the risk of local complications among patients with haemotoxic snakebite envenomation treated at a teaching hospital in southern India: a randomised, non-inferiority trial

Clinically directed initiation versus routine use of amoxicillin-clavulanate and the risk of local complications among patients with haemotoxic snakebite envenomation treated at a teaching hospital in southern India: a randomised, non-inferiority trial

Objective Amoxicillin-clavulanate is commonly used to prevent infections following snakebites despite the lack of clinical evidence. We aimed to demonstrate that clinically directed initiation of amoxicillin-clavulanate would be non-inferior to routine use in this setting.Design Open-label, randomis...

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Main Authors: Tamilarasu Kadhiravan, Chanaveerappa Bammigatti, Akinchan Bhardwaj, Aditya Gautam, Malayil B Indu, Paramasivam Sabitha, Surendran Deepanjali, Bettadpura Shamanna Suryanarayana
Format: Article
Language:English
Published: BMJ Publishing Group 2025-06-01
Series:BMJ Open
Online Access:https://bmjopen.bmj.com/content/15/6/e094409.full
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https://bmjopen.bmj.com/content/15/6/e094409.full

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