Protocol for identifying key genes using network-based approach as an alternative to differential expression analysis

Summary: In a variety of biological contexts, characterizing genes associated with disease etiology and mediating global transcriptomic change is a key initial step. Here, we present a protocol to identify such key genes using our tool “PathExt,” a tool that implements a network-based approach. We d...

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Bibliographic Details
Main Authors: Piyush Agrawal, Sridhar Hannenhalli
Format: Article
Language:English
Published: Elsevier 2024-12-01
Series:STAR Protocols
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Online Access:http://www.sciencedirect.com/science/article/pii/S2666166724006373
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