The role of autophagy inhibition in the enhanced cytotoxicity of temozolomide on melanoma cell lines

Background. Despite advantages in treatment of metastatic melanoma it remains resistant to current therapy. Recent evidence indicates that tumor cells could overcome death through autophagy, a process that degrades cellular proteins and organelles to maintain cellular biosynthesis during nutrient de...

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Main Authors: O. O. Ryabaya, A. N. Inshakov, A. A. Malysheva, I. S. Abramov, N. V. Sholina, D. A. Khochenkov, E. V. Stepanova
Format: Article
Language:Russian
Published: ABV-press 2017-10-01
Series:Успехи молекулярной онкологии
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Online Access:https://umo.abvpress.ru/jour/article/view/104
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