Spatial transcriptomics and scRNA-seq: decoding tumor complexity and constructing prognostic models in colorectal cancer

Abstract Introduction Recent advancements in transcriptomic analysis, combined with single-cell RNA sequencing (scRNA-seq) and spatial transcriptomics, have deepened our understanding of the tumor microenvironment and cellular heterogeneity, laying the groundwork for personalized therapies. The aim...

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Bibliographic Details
Main Authors: Wei Song, Yatao Wang, Min Zhou, Fengqin Guo, Yanliang Liu
Format: Article
Language:English
Published: BMC 2025-08-01
Series:Human Genomics
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Online Access:https://doi.org/10.1186/s40246-025-00805-x
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