Assessment of the Lipophilicity of Indole Derivatives of Betulin and Their Toxicity in a Zebrafish Model

Assessment of the Lipophilicity of Indole Derivatives of Betulin and Their Toxicity in a Zebrafish Model

There are scientific studies indicating that the attachment of an indole moiety to the triterpene scaffold can lead to increased anticancer potential. Lipophilicity is one of the factors that may influence biological properties and is therefore an important parameter to determine for newly obtained...

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Bibliographic Details
Main Authors: Zuzanna Rzepka, Katarzyna Bober-Majnusz, Justyna Magdalena Hermanowicz, Ewa Bębenek, Elwira Chrobak, Arkadiusz Surażyński, Dorota Wrześniok
Format: Article
Language:English
Published: MDPI AG 2024-09-01
Series:Molecules
Subjects:
triterpenoids
lipophilicity
indole
RP-TLC
zebrafish
Online Access:https://www.mdpi.com/1420-3049/29/18/4408
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