Immunopeptidomics for autoimmunity: unlocking the chamber of immune secrets

Abstract T cells mediate pathogenesis of several autoimmune disorders by recognizing self-epitopes presented on Major Histocompatibility Complex (MHC) or Human Leukocyte Antigen (HLA) complex. The majority of autoantigens presented to T cells in various autoimmune disorders are not known, which has...

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Bibliographic Details
Main Authors: Sanya Arshad, Benjamin Cameron, Alok V. Joglekar
Format: Article
Language:English
Published: Nature Portfolio 2025-01-01
Series:npj Systems Biology and Applications
Online Access:https://doi.org/10.1038/s41540-024-00482-x
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